TIRAP 抗体
(Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
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69 results
TIRAP
适用: 人
WB
宿主: 兔
Monoclonal
R09-5Z2R09-5Z2
unconjugated
Recombinant Antibody
TIRAP
适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠, 兔
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our TIRAP 抗体
: "Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 52-66, (2019) (PubMed).: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).
: "Heterodimer-specific TLR2 stimulation results in divergent functional outcomes in B-cell precursor acute lymphoblastic leukemia." in: European journal of immunology, Vol. 45, Issue 7, pp. 1980-90, (2015) (PubMed).
: "Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 5, pp. 437-47, (2013) (PubMed).
: "Phosphatidylinositol 4-phosphate 5-kinase ? facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein ..." in: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5645-59, (2013) (PubMed).
: "Preferential expression and function of Toll-like receptor 3 in human astrocytes." in: Journal of neuroimmunology, Vol. 159, Issue 1-2, pp. 12-9, (2005) (PubMed).
: "Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP." in: Blood, Vol. 103, Issue 6, pp. 2229-37, (2004) (PubMed).
: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).
: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, (2004) (PubMed).
: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).
Aliases for TIRAP 抗体
toll-interleukin 1 receptor (TIR) domain containing adaptor protein (tirap) 抗体TIR domain containing adaptor protein (TIRAP) 抗体
toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog (tirap.L) 抗体
TIR domain containing adaptor protein (Tirap) 抗体
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap) 抗体
AA407980 抗体
BACTS1 抗体
C130027E04Rik 抗体
mal 抗体
Mal 抗体
MyD88-2 抗体
Tlr4ap 抗体
wyatt 抗体
Wyatt 抗体
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