This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008].
Boström, Wu, Jedrychowski, Korde, Ye, Lo, Rasbach, Boström, Choi, Long, Kajimura, Zingaretti, Vind, Tu, Cinti, Højlund, Gygi, Spiegelman: "A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis." in: Nature, Vol. 481, Issue 7382, pp. 463-8, (2012) (PubMed).
Aliases for TIMP4 蛋白
TIMP metallopeptidase inhibitor 4 (TIMP4) 蛋白 TIMP metallopeptidase inhibitor 4, tandem duplicate 3 (timp4.3) 蛋白 tissue inhibitor of metalloproteinase 4 (Timp4) 蛋白 TIMP metallopeptidase inhibitor 4 (Timp4) 蛋白 TIMP-4 蛋白 TIMP4 蛋白 timp4 蛋白