The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known.
Smit, Riggs: "Tiggers and DNA transposon fossils in the human genome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 4, pp. 1443-8, (1996) (PubMed).
Aliases for TIGD1 抗体
tigger transposable element derived 1 (TIGD1) 抗体 EEYORE 抗体