(T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Artym, Swatkoski, Matsumoto, Campbell, Petrie, Dimitriadis, Li, Mueller, Bugge, Gucek, Yamada: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).
Aliases for TIAM2 抗体
T-cell lymphoma invasion and metastasis 2 (TIAM2) 抗体 T cell lymphoma invasion and metastasis 2 (Tiam2) 抗体 T-cell lymphoma invasion and metastasis 2a (tiam2a) 抗体 T-cell lymphoma invasion and metastasis 2 (Tiam2) 抗体 T-lymphoma invasion and metastasis-inducing protein 2 (LOC100598161) 抗体 3000002F19Rik 抗体 mKIAA2016 抗体 STEF 抗体 TIAM-2 抗体 TIAM2 抗体