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THEMIS 产品

(Thymocyte Selection Associated (THEMIS))
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Featured THEMIS Categories

THEMIS 抗体

High quality antibodies with extensive validation data.

THEMIS ELISA试剂盒

Reliable ELISA kits for a wide range of species.

THEMIS 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended THEMIS 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (3)
Cat. No. ABIN1714633
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7166179
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN571144
Quantity 100 μg
Datasheet Datasheet

Recommended THEMIS ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959950
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959951
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1152607
Quantity 96 tests
Datasheet Datasheet

Recommended THEMIS 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2752947
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3073988
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3136150
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our THEMIS Products

Paster, Bruger, Katsch, Grégoire, Roncagalli, Fu, Gascoigne, Nika, Cohnen, Feller, Simister, Molder, Cordoba, Dushek, Malissen, Acuto: "A THEMIS:SHP1 complex promotes T-cell survival." in: The EMBO journal, Vol. 34, Issue 3, pp. 393-409, (2015) (PubMed).

Fu, Vallée, Rybakin, McGuire, Ampudia, Brockmeyer, Salek, Fallen, Hoerter, Munshi, Huang, Hu, Fox, Sauer, Acuto, Gascoigne: "Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling." in: Nature immunology, Vol. 10, Issue 8, pp. 848-56, (2009) (PubMed).

Johnson, Aravind, Shulzhenko, Morgun, Choi, Crockford, Lambe, Domaschenz, Kucharska, Zheng, Vinuesa, Lenardo, Goodnow, Cornall, Schwartz: "Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection." in: Nature immunology, Vol. 10, Issue 8, pp. 831-9, (2009) (PubMed).

Lesourne, Uehara, Lee, Song, Li, Pinkhasov, Zhang, Weng, Wildt, Wang, Bosselut, Love: "Themis, a T cell-specific protein important for late thymocyte development." in: Nature immunology, Vol. 10, Issue 8, pp. 840-7, (2009) (PubMed).

Patrick, Oda, Hayakawa, Sato, Eshima, Kirikae, Iemura, Shirai, Abe, Natsume, Sasazuki, Suzuki: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, (2009) (PubMed).

Synonyms and alternative names related to THEMIS

thymocyte selection associated (THEMIS), thymocyte selection associated (Themis), thymocyte selection associated (themis), A430108D01, bA325O24.3, bA325O24.4, BB160712, C6orf190, C6orf207, C9H6ORF190, E430004N04Rik, GASP, Gasp, im:7138580, SPOT, thylex, TSEPA, Tsepa, tsepa

Protein level used designations for THEMIS

  • thymocyte selection associated
  • thymocyte selection pathway associated
  • GRB2-associated protein
  • protein THEMIS
  • signaling phosphoprotein specific for T cells
  • thymocyte expressed molecule involved in selection
  • thymocyte-expressed molecule involved in selection
  • grb2-associating protein
  • protein thylex
  • thymus lymphocyte exclusively expressed
  • Thymocyte-expressed molecule involved in selection
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