TGS1 抗体
(Trimethylguanosine Synthase 1 (TGS1))
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation (By similarity).
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TGS1
适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 豚鼠, 兔
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our TGS1 抗体
: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).: "Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus." in: Biochemical and biophysical research communications, Vol. 309, Issue 1, pp. 44-51, (2003) (PubMed).
: "Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 18, pp. 11836-41, (2002) (PubMed).
Aliases for TGS1 抗体
trimethylguanosine synthase 1 (TGS1) 抗体trimethylguanosine synthase 1 (Tgs1) 抗体
trimethylguanosine synthase 1 L homeolog (tgs1.L) 抗体
D4Ertd800e 抗体
NCOA6IP 抗体
Ncoa6ip 抗体
PIMT 抗体
Pimt 抗体
PIPMT 抗体
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