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TFE3 ELISA试剂盒

(Transcription Factor E3 (TFE3))

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3, SMAD3, and LEF-1, and is involved in TGF-beta-induced transcription, playing important roles in cell growth, proliferation, and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1)\; it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, RCC17-TFE3, PSF-TFE3, NonO (p54nrb)-TFE3 and ASPL-TFE3.[provided by RefSeq, Dec 2009].

recommended

TFE3 ELISA 试剂盒 (ABIN6960060)

TFE3 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate

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recommended

TFE3 ELISA 试剂盒 (ABIN5648528)

TFE3 适用: 人, 小鼠 Colorimetric DNA-Binding ELISA

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Find TFE3 ELISA试剂盒 for a variety of species such as anti-Human TFE3, anti-Mouse TFE3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular TFE3 ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

TFE3 ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6960060

Quantity 96 tests

Datasheet Datasheet

TFE3 ELISA 试剂盒

Reactivity Human, Mouse

Analytical Method Qualitative DNA-Binding ELISA

Validations

Cat. No. ABIN5648528

Quantity 96 tests

Datasheet Datasheet

Aliases for TFE3 ELISA试剂盒

transcription factor binding to IGHM enhancer 3 (TFE3) ELISA试剂盒
transcription factor E3 (Tfe3) ELISA试剂盒
transcription factor binding to IGHM enhancer 3 (Tfe3) ELISA试剂盒
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TFE3 ELISA试剂盒 by 适用

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Popular TFE3 ELISA试剂盒

Aliases for TFE3 ELISA试剂盒

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