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TES 产品

(Testis Derived Transcript (3 LIM Domains) (TES))
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011].

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Featured TES Categories

TES 抗体

High quality antibodies with extensive validation data.

TES ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TES 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TES 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN565232
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application IHC
Validations
  • (4)
Cat. No. ABIN7263067
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7171794
Quantity 100 μg
Datasheet Datasheet

Recommended TES ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6970591
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1161214
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1161212
Quantity 96 tests
Datasheet Datasheet

Recommended TES 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322483
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125338
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3073880
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TES Products

Danielsson, Wiking, Mahdessian, Skogs, Ait Blal, Hjelmare, Stadler, Uhlén, Lundberg: "RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins." in: Journal of proteome research, Vol. 12, Issue 1, pp. 299-307, (2013) (PubMed).

Qiu, Zhu, Yuan, Yan, Yang, Kong: "Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer." in: Cancer science, Vol. 101, Issue 5, pp. 1255-60, (2010) (PubMed).

Gunduz, Gunduz, Beder, Nagatsuka, Fukushima, Sutcu, Delibas, Yamanaka, Shimizu, Nagai: "Downregulation of TESTIN and its association with cancer history and a tendency toward poor survival in head and neck squamous cell carcinoma." in: Archives of otolaryngology--head & neck surgery, Vol. 135, Issue 3, pp. 254-60, (2009) (PubMed).

Boëda, Briggs, Higgins, Garvalov, Fadden, McDonald, Way: "Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding." in: Molecular cell, Vol. 28, Issue 6, pp. 1071-82, (2007) (PubMed).

Synonyms and alternative names related to TES

testin LIM domain protein (TES), testin LIM domain protein L homeolog (tes.L), testis derived transcript (3 LIM domains) (tes), testin LIM domain protein (tes), testis derived transcript (3 LIM domains) (TES), testis derived transcript (Tes), testin LIM domain protein (Tes), D6Ertd352e, DKFZp469E2320, TES, Tes1, Tes2, TESS, tess, TESS-2, tess-2, Testin, testin2, xtes, zgc:92091

Protein level used designations for TES

  • testin
  • xtes
  • testis derived transcript (3 LIM domains)
  • TES1/TES2
  • testin 2
  • Testin-like protein
  • testis derived transcript
  • LOW QUALITY PROTEIN: testin
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