(TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 140kDa (TAF3))
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1\; MIM 313650) comprises the TATA box-binding protein (TBP\; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009].