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TAB1 ELISA试剂盒

(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

2 results

TAB1 适用: 人 Colorimetric Sandwich ELISA 0.313 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
产品编号 ABIN6970603
 
TAB1 适用: 小鼠 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Plasma, Serum
产品编号 ABIN6229502
 
  • 类型 Kit
    • Kit
  • 应用范围 ELISA
    • ELISA
  • 适用
    • Human
    • Mouse
  • 图像
  • 实验类型
    • Sandwich ELISA
  • Analytical Method
    • Quantitative
  • 检测方法
    • Colorimetric
  • Plate
    • Pre-coated
  • 标记
    • 非结合性
  • 样本
    • Plasma
    • Serum
    • Tissue Homogenate
  • Supplier
    • Abbexa
    • antibodies-online

Aliases for TAB1 ELISA试剂盒

TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1) ELISA试剂盒
TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) ELISA试剂盒
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