This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011].
custom-made
SYP
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
SYP
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Caviness, Lue, Beach, Hentz, Adler, Sue, Sadeghi, Driver-Dunckley, Evidente, Sabbagh, Shill, Walker: "Parkinson's disease, cortical dysfunction, and alpha-synuclein." in: Movement disorders : official journal of the Movement Disorder Society, Vol. 26, Issue 8, pp. 1436-42, (2011) (PubMed).
Andreyeva, Leshchynska, Knepper, Betzel, Redecke, Sytnyk, Schachner: "CHL1 is a selective organizer of the presynaptic machinery chaperoning the SNARE complex." in: PLoS ONE, Vol. 5, Issue 8, pp. e12018, (2010) (PubMed).