This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Latest Publications for our Surfactant Protein A1 蛋白
Su, Shi, Liu, Huang, Huang, Nie: "Metabolic profiling of asthma in mice and the interventional effects of SPA using liquid chromatography and Q-TOF mass spectrometry." in: Molecular bioSystems, Vol. 13, Issue 6, pp. 1172-1181, (2018) (PubMed).