SUPV3L1 抗体
(Suppressor of Var1, 3-Like 1 (SUPV3L1))
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria\; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA (By similarity).
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Latest Publications for our SUPV3L1 抗体
: "Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance." in: Nucleic acids research, Vol. 38, Issue 1, pp. 279-98, (2010) (PubMed).: "Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 20812-21, (2009) (PubMed).
: "Role of SUV3 helicase in maintaining mitochondrial homeostasis in human cells." in: The Journal of biological chemistry, Vol. 283, Issue 40, pp. 27064-73, (2008) (PubMed).
: "The layered structure of human mitochondrial DNA nucleoids." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).
: "Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality." in: Mechanisms of ageing and development, Vol. 128, Issue 11-12, pp. 609-17, (2007) (PubMed).
Aliases for SUPV3L1 抗体
Suv3 like RNA helicase (SUPV3L1) 抗体suppressor of var1, 3-like 1 (S. cerevisiae) (Supv3l1) 抗体
Suv3 like RNA helicase (Supv3l1) 抗体
SUV3-like helicase (supv3l1) 抗体
6330443E10Rik 抗体
SUV3 抗体
wu:fc19b02 抗体
wu:fe37e06 抗体
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