Suppression of Tumorigenicity 14 抗体
(Suppression of Tumorigenicity 14 (ST14))
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008].
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Latest Publications for our Suppression of Tumorigenicity 14 抗体
: "Developmental mechanisms driving complex tooth shape in reptiles." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).: "Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis." in: PLoS genetics, Vol. 15, Issue 1, pp. e1007882, (2019) (PubMed).
: "Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis." in: The Journal of biological chemistry, Vol. 292, Issue 26, pp. 10801-10812, (2017) (PubMed).
: "Matriptase zymogen supports epithelial development, homeostasis and regeneration." in: BMC biology, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin." in: The Journal of biological chemistry, Vol. 291, Issue 6, pp. 2577-82, (2016) (PubMed).
: "Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling." in: Nature communications, Vol. 6, pp. 6776, (2015) (PubMed).
: "Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors." in: Oncogene, Vol. 34, Issue 35, pp. 4664-72, (2015) (PubMed).
: "Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma." in: The Journal of investigative dermatology, Vol. 135, Issue 9, pp. 2283-91, (2015) (PubMed).
: "Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survival." in: PLoS genetics, Vol. 10, Issue 7, pp. e1004470, (2015) (PubMed).
: "Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium." in: Journal of virology, Vol. 87, Issue 8, pp. 4237-51, (2013) (PubMed).
Aliases for Suppression of Tumorigenicity 14 抗体
suppression of tumorigenicity 14 (ST14) 抗体amyloid beta precursor like protein 2 (APLP2) 抗体
suppression of tumorigenicity 14 L homeolog (st14.L) 抗体
suppression of tumorigenicity 14 (colon carcinoma) (St14) 抗体
suppression of tumorigenicity 14 (St14) 抗体
suppression of tumorigenicity 14 (colon carcinoma) a (st14a) 抗体
suppression of tumorigenicity 14 (colon carcinoma) b (st14b) 抗体
suppression of tumorigenicity 14 S homeolog (st14.S) 抗体
APLP-2 抗体
APPH 抗体
APPL2 抗体
CDEBP 抗体
Epithin 抗体
HAI 抗体
hai 抗体
matriptase 抗体
mCAP3 抗体
MT-SP1 抗体
mt-sp1 抗体
MTSP1 抗体
mtsp1 抗体
PRSS14 抗体
prss14 抗体
Prss14 抗体
SNC19 抗体
snc19 抗体
st14 抗体
st14-a 抗体
st14-b 抗体
st14a 抗体
st14b 抗体
TADG15 抗体
tadg15 抗体
tmprss1 抗体
TMPRSS14 抗体
Tmprss14 抗体
wu:fi41g07 抗体
wu:fl72f01 抗体
XMT-SP1 抗体
zgc:136950 抗体
zgc:152656 抗体
zgc:152657 抗体
zgc:152947 抗体
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