This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
Read, Brownell, Gladysheva, Hottelet, Parent, Coggins, Pierce, Podust, Luo, Chau, Palombella: "Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha." in: Molecular and cellular biology, Vol. 20, Issue 7, pp. 2326-33, (2000) (PubMed).
Kitagawa, Skowyra, Elledge, Harper, Hieter: "SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex." in: Molecular cell, Vol. 4, Issue 1, pp. 21-33, (1999) (PubMed).
Aliases for SUGT1 抗体
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone (SUGT1) 抗体 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) (Sugt1) 抗体 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone (Sugt1) 抗体 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) pseudogene (LOC100402050) 抗体 suppressor of G2 allele of SKP1 homolog (LOC100512856) 抗体 protein SGT1 homolog (LOC100631434) 抗体 protein SGT1 homolog (LOC100645570) 抗体 SGT1 disease resistance protein homolog1 (IDP1602) 抗体 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone (sgut1) 抗体 2410174K12Rik 抗体 Aa1114 抗体 SGT1 抗体 sugt1 抗体 wu:fd45a02 抗体 zgc:103668 抗体