CYP3A4 抗体
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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recommended
CYP3A4 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p), ICC, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
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Popular CYP3A4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN969512
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, IF (p), IHC (p), ICC, IF (cc), IHC (fro)
Validations
- (1)
- (4)
Cat. No.
ABIN733793
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (5)
Cat. No.
ABIN7260509
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN514838
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF, IHC (p), EIA
Validations
- (7)
Cat. No.
ABIN1106886
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (1)
- (3)
Cat. No.
ABIN947776
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7149259
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (3)
Cat. No.
ABIN185606
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF
Validations
- (1)
- (3)
Cat. No.
ABIN652422
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Human, Mouse, Rat
Application
WB, IF (p), IHC (p)
Validations
- (2)
Cat. No.
ABIN680138
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7435469
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7149264
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7127448
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6754944
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6754943
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our CYP3A4 抗体
: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." in: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).: "Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver." in: International journal of molecular sciences, Vol. 20, Issue 18, (2019) (PubMed).
: "Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine." in: PLoS ONE, Vol. 13, Issue 3, pp. e0194979, (2018) (PubMed).
: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).
: "Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 47, Issue 11, pp. 951-961, (2017) (PubMed).
: "Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice." in: Life sciences, Vol. 95, Issue 1, pp. 1-8, (2014) (PubMed).
: "Dermal xenobiotic metabolism: a comparison between native human skin, four in vitro skin test systems and a liver system." in: Skin pharmacology and physiology, Vol. 27, Issue 5, pp. 263-75, (2014) (PubMed).
: "Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." in: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).
: "Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome." in: Pharmacology research & perspectives, Vol. 2, Issue 5, pp. e00053, (2014) (PubMed).
: "Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line." in: British journal of pharmacology, Vol. 169, Issue 1, pp. 21-33, (2013) (PubMed).
Aliases for CYP3A4 抗体
cytochrome P450 family 3 subfamily A member 4 (CYP3A4) 抗体cytochrome P450 family 3 subfamily A member 43 (CYP3A43) 抗体
cytochrome P450 3A4 (PTRG_01782) 抗体
cytochrome P450 3A4 (PTRG_06060) 抗体
cytochrome P450 family 3 subfamily A member 4 (cyp3a4) 抗体
cytochrome P450, subfamily IIIA, polypeptide 4 (CYP3A4) 抗体
cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 (CYP3A4) 抗体
cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) 抗体
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