Streptolysin O 蛋白
(Streptolysin O (SLO))
Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
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8 results :
SLO
宿主: Streptococcus pyogenes
宿主: 大肠杆菌（E. Coli）
Recombinant
> 98 % by SDS-PAGE
ELISA, WB, SDS
Active
3 references
SLO
宿主: Streptococcus
宿主: Streptococcus pyogenes (Streptococcus hemolyticus)
Native
> 95 % pure
ELISA, LETIA
Active
SLO
宿主: Streptococcus
宿主: Streptococcus pyogenes (Streptococcus hemolyticus)
Native
> 95 % pure
ELISA, WB, SDS
SLO
宿主: Streptococcus pyogenes
宿主: Bacteria
Native
> 95 % (SDS-PAGE)
ELISA, WB
Latest Publications for our Streptolysin O 蛋白
: "GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus." in: Nature cell biology, Vol. 10, Issue 10, pp. 1135-45, (2008) (PubMed).: "Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 6, pp. 3185-90, (2001) (PubMed).
: "The family of thiol-activated, cholesterol-binding cytolysins." in: Toxicon : official journal of the International Society on Toxinology, Vol. 39, Issue 11, pp. 1681-9, (2001) (PubMed).
Aliases for Streptolysin O 蛋白
streptolysin O (slo) 蛋白streptolysin O (M6_Spy0188) 蛋白
Streptolysin O (slo) 蛋白
Thiol-activated cytolysin (slo) 蛋白
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