(Serine/threonine Kinase Receptor Associated Protein (STRAP))
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein (By similarity).
Datta, Chytil, Gorska, Moses: "Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling." in: The Journal of biological chemistry, Vol. 273, Issue 52, pp. 34671-4, (1999) (PubMed).
Aliases for STRAP 抗体
serine/threonine kinase receptor associated protein (STRAP) 抗体 tetratricopeptide repeat domain 5 (TTC5) 抗体 serine/threonine kinase receptor associated protein (strap) 抗体 serine/threonine kinase receptor associated protein L homeolog (strap.L) 抗体 serine/threonine kinase receptor associated protein S homeolog (strap.S) 抗体 serine/threonine kinase receptor associated protein (Strap) 抗体 AW557906 抗体 C78091 抗体 C79202 抗体 MAWD 抗体 mawd 抗体 PT-WD 抗体 pt-wd 抗体 UNRIP 抗体 unrip 抗体 Unrip 抗体 zgc:56677 抗体 zgc:77604 抗体