STK4 抗体
(serine/threonine Kinase 4 (STK4))
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008].
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Latest Publications for our STK4 抗体
: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).: "Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 3, pp. M110.001784, (2011) (PubMed).
: "Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 35029-38, (2010) (PubMed).
: "Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells." in: Cancer research, Vol. 68, Issue 7, pp. 2266-74, (2008) (PubMed).
: "Merlin is a potent inhibitor of glioma growth." in: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).
: "Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma." in: Molecular carcinogenesis, Vol. 46, Issue 10, pp. 865-71, (2007) (PubMed).
: "Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30836-44, (2007) (PubMed).
: "The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1." in: The EMBO journal, Vol. 26, Issue 21, pp. 4523-34, (2007) (PubMed).
Aliases for STK4 抗体
serine/threonine kinase 4 (STK4) 抗体serine/threonine kinase 4 (Stk4) 抗体
serine/threonine kinase 4 S homeolog (stk4.S) 抗体
AI447339 抗体
AU020804 抗体
Kas-2 抗体
KRS2 抗体
krs2 抗体
MST1 抗体
Mst1 抗体
mst1 抗体
TIIAC 抗体
YSK3 抗体
Ysk3 抗体
ysk3 抗体
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