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STK38 产品

(serine/threonine Kinase 38 (STK38))

Categories

Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).

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Featured STK38 Categories

STK38 抗体

High quality antibodies with extensive validation data.

STK38 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STK38 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (7)
Cat. No. ABIN7199721
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), IP
Validations
  • (1)
  • (8)
Cat. No. ABIN7199720
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (2)
  • (7)
Cat. No. ABIN564920
Quantity 100 μg
Datasheet Datasheet

Recommended STK38 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232491
Quantity 96 tests
Datasheet Datasheet

Recommended STK38 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5569671
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321700
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321698
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our STK38 Products

Klimek, Jahnke, Wördehoff, Kathage, Stadel, Behrends, Hergovich, Höhfeld: "The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1866, Issue 10, pp. 1556-1566, (2020) (PubMed).

Tame, Raaijmakers, Afanasyev, Medema: "Chromosome misalignments induce spindle-positioning defects." in: EMBO reports, Vol. 17, Issue 3, pp. 317-25, (2016) (PubMed).

Fukasawa, Enomoto, Miyagawa: "Serine-Threonine Kinase 38 regulates CDC25A stability and the DNA damage-induced G2/M checkpoint." in: Cellular signalling, Vol. 27, Issue 8, pp. 1569-75, (2015) (PubMed).

Yan, Chu, Qin, Wang, Liu, Jin, Zhang, Gomez, Hergovich, Chen, He, Gao, Yao: "Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis." in: Scientific reports, Vol. 5, pp. 10449, (2015) (PubMed).

Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: "Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages." in: Nature communications, Vol. 6, pp. 7167, (2015) (PubMed).

Cook, Hoa, Gomez, Gomez, Hergovich: "Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling." in: Cellular signalling, Vol. 26, Issue 8, pp. 1657-67, (2014) (PubMed).

Zhou, Adolfs, Pijnappel, Fuller, Van der Schors, Li, Sugden, Smit, Hergovich, Pasterkamp: "MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis." in: Molecular and cellular biology, Vol. 31, Issue 17, pp. 3603-15, (2011) (PubMed).

Kohler, Schmitz, Cornils, Hemmings, Hergovich: "Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases." in: Molecular and cellular biology, Vol. 30, Issue 18, pp. 4507-20, (2010) (PubMed).

Devroe, Erdjument-Bromage, Tempst, Silver: "Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24444-51, (2004) (PubMed).

Tamaskovic, Bichsel, Rogniaux, Stegert, Hemmings: "Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 6710-8, (2003) (PubMed).

Synonyms and alternative names related to STK38

serine/threonine kinase 38 (STK38), serine/threonine kinase 38 (Stk38), serine/threonine kinase 38 S homeolog (stk38.S), serine/threonine kinase 38b (stk38b), serine/threonine kinase 38a (stk38a), 5830476G13Rik, 9530097A09Rik, AA617404, NDR, NDR1, Ndr1, si:ch1073-272h17.2, trc, wu:fj80h03, zgc:55572

Protein level used designations for STK38

  • NDR1 protein kinase
  • Ndr Ser/Thr kinase-like protein
  • nuclear Dbf2-related 1
  • nuclear Dbf2-related kinase 1
  • serine threonine protein kinase
  • serine/threonine-protein kinase 38
  • nuclear DBF2-related kinase 1
  • tricornered
  • stk38
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