This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008].
custom-made
SRY
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Holt, Zhang, Binia, Dixon, Vandiedonck, Cookson, Knight, Moffatt: "Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 4, pp. 1054-62.e1-2, (2011) (PubMed).
Aliases for SRY 蛋白
sex determining region Y (SRY) 蛋白 sex determining region Y (Sry) 蛋白 sex determining region of Chr Y (Sry) 蛋白 SRXX1 蛋白 SRXY1 蛋白 SRY 蛋白 Sry1 蛋白 Sry3BI 蛋白 SRYGENE 蛋白 TDF 蛋白 Tdf 蛋白 TDY 蛋白 Tdy 蛋白