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SRRT 蛋白

(Serrate RNA Effector Molecule Homolog (SRRT))
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA)\; however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).

3 results

SRRT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AA, AP, WB
产品编号 ABIN1345737
 
SRRT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2714949
 
SRRT 宿主: Chinese Hamster 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1635251
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
    • Western Blotting (WB)
  • 适用
    • Human
    • Chinese Hamster
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • 抗原表位
    • AA 1-306
    • AA 1-429
    • Transcript Variant 1
  • 标记
    • GST tag
    • His tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
  • Supplier
    • CUSABIO
    • OriGene
    • antibodies-online

Aliases for SRRT 蛋白

Arsenic resistance protein 2 (Ars2) 蛋白
serrate, RNA effector molecule S homeolog (srrt.S) 蛋白
serrate, RNA effector molecule (SRRT) 蛋白
serrate RNA effector molecule homolog (Arabidopsis) (Srrt) 蛋白
serrate, RNA effector molecule (Srrt) 蛋白
serrate RNA effector molecule homolog (Arabidopsis) (srrt) 蛋白
2810019G02Rik 蛋白
anon-WO0118547.166 蛋白
ars2 蛋白
ARS2 蛋白
Ars2 蛋白
ars2-A 蛋白
ASR2 蛋白
Asr2 蛋白
ASR2A 蛋白
ASR2B 蛋白
ASR2C 蛋白
ASR2D 蛋白
CG7843 蛋白
CHUNP6881 蛋白
Dmel\\CG7843 蛋白
MGC92060 蛋白
serrate 蛋白
zgc:92060 蛋白
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