The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012].
Spinazzi, Radaelli, Horré, Arranz, Gounko, Agostinis, Maia, Impens, Morais, Lopez-Lluch, Serneels, Navas, De Strooper: "PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 1, pp. 277-286, (2019) (PubMed).