SPTLC2 抗体
(serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
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Latest Publications for our SPTLC2 抗体
: "ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 12, pp. 3728-33, (2015) (PubMed).: "Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).
: "Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8186-91, (2009) (PubMed).
: "The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase." in: The Plant cell, Vol. 18, Issue 12, pp. 3576-93, (2007) (PubMed).
: "Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?" in: The Biochemical journal, Vol. 405, Issue 1, pp. 157-64, (2007) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 7, pp. 3491-6, (2000) (PubMed).
Aliases for SPTLC2 抗体
serine palmitoyltransferase long chain base subunit 2 (SPTLC2) 抗体serine palmitoyltransferase 2 (LOC100446763) 抗体
serine palmitoyltransferase long chain base subunit 2 (sptlc2) 抗体
serine palmitoyltransferase, long chain base subunit 2 S homeolog (sptlc2.S) 抗体
serine palmitoyltransferase, long chain base subunit 2a (sptlc2a) 抗体
serine palmitoyltransferase, long chain base subunit 2 (Sptlc2) 抗体
serine palmitoyltransferase long chain base subunit 2 (Sptlc2) 抗体
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