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SPPL2B 抗体

(Signal Peptide Peptidase-Like 2B (SPPL2B))
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

12 results :

SPPL2B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN634985
 
SPPL2B 适用: 人, 大鼠, Cow, 马, 小鼠, Pig, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN2782090
 
SPPL2B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6738138
 
SPPL2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169627
 
SPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53139 unconjugated
产品编号 ABIN6243975
 
SPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53138 unconjugated
产品编号 ABIN6243976
 
SPPL2B 适用: 人 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386177
 
SPPL2B 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7169629
 
SPPL2B 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7169630
 
SPPL2B 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7169628
 
SPPL2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6752476
 
SPPL2B 适用: 人, 大鼠, 小鼠 ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7096696
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (IF)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 适用
    • Human
    • Cow
    • Mouse
    • Rat
    • Dog
    • Guinea Pig
    • Horse
    • Pig
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
  • 克隆形成能力
    • Polyclonal
  • 克隆
    • RB53138
    • RB53139
  • 抗原表位
    • AA 492-592
    • N-Term
    • AA 126-160
    • AA 196-229
    • AA 53-102
    • AA 55-135
    • AA 93-142
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
  • 抗体亚型
    • IgG
    • Ig Fraction
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Aviva Systems Biology

Latest Publications for our SPPL2B 抗体

Del Campo, Hoozemans, Dekkers, Rozemuller, Korth, Müller-Schiffmann, Scheltens, Blankenstein, Jimenez, Veerhuis, Teunissen: "BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease." in: Neurobiology of aging, Vol. 35, Issue 7, pp. 1596-604, (2014) (PubMed).

Friedmann, Lemberg, Weihofen, Dev, Dengler, Rovelli, Martoglio: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).

Grigorenko, Moliaka, Korovaitseva, Rogaev: "Novel class of polytopic proteins with domains associated with putative protease activity." in: Biochemistry. Biokhimii?a, Vol. 67, Issue 7, pp. 826-35, (2002) (PubMed).

Weihofen, Binns, Lemberg, Ashman, Martoglio: "Identification of signal peptide peptidase, a presenilin-type aspartic protease." in: Science (New York, N.Y.), Vol. 296, Issue 5576, pp. 2215-8, (2002) (PubMed).

Nagase, Kikuno, Ishikawa, Hirosawa, Ohara: "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 2, pp. 143-50, (2000) (PubMed).

Aliases for SPPL2B 抗体

signal peptide peptidase-like 2 (sppl2) 抗体
signal peptide peptidase like 2B (sppl2b) 抗体
signal peptide peptidase like 2B S homeolog (sppl2b.S) 抗体
signal peptide peptidase like 2B (SPPL2B) 抗体
signal peptide peptidase like 2B (Sppl2b) 抗体
signal peptide peptidase-like 2B (Sppl2b) 抗体
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