SP100 抗体
(SP100 Nuclear Antigen (SP100))
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene\; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011].
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Latest Publications for our SP100 抗体
: "The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169648, (2017) (PubMed).: "Quantification of the host response proteome after herpes simplex virus type 1 infection." in: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).
: "Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1." in: Viruses, Vol. 7, Issue 6, pp. 2884-907, (2015) (PubMed).
: "Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity." in: PLoS pathogens, Vol. 10, Issue 1, pp. e1003863, (2014) (PubMed).
: "Sp100 provides intrinsic immunity against human papillomavirus infection." in: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).
: "Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100." in: The Journal of general virology, Vol. 92, Issue Pt 7, pp. 1532-8, (2011) (PubMed).
: "Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle." in: Journal of virology, Vol. 85, Issue 18, pp. 9447-58, (2011) (PubMed).
Aliases for SP100 抗体
SP100 nuclear antigen (SP100) 抗体nuclear antigen Sp100 (Sp100) 抗体
SP100 nuclear antigen (Sp100) 抗体
nuclear autoantigen Sp-100 (LOC101120993) 抗体
A430075G10Rik 抗体
lysp100b 抗体
SP100 抗体
SP140 抗体
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