SNCA 抗体
(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
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Latest Publications for our SNCA 抗体
: "Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease." in: International journal of pharmaceutics, Vol. 579, pp. 119148, (2020) (PubMed).: "Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin." in: Journal of Alzheimer's disease : JAD, Vol. 69, Issue 2, pp. 463-478, (2019) (PubMed).
: "Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease." in: Life sciences, Vol. 223, pp. 158-165, (2019) (PubMed).
: "An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with α-Synucleinopathy." in: Cell transplantation, Vol. 27, Issue 5, pp. 831-839, (2019) (PubMed).
: "Apelin-36 mitigates MPTP/MPP+-induced neurotoxicity: Involvement of α-synuclein and endoplasmic reticulum stress." in: Brain research, Vol. 1721, pp. 146334, (2019) (PubMed).
: "Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy." in: Translational neurodegeneration, Vol. 8, pp. 24, (2019) (PubMed).
: "Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide." in: Neuron, (2018) (PubMed).
: "Quantitative Proteomics Reveals the Regulatory Networks of Circular RNA CDR1as in Hepatocellular Carcinoma Cells." in: Journal of proteome research, Vol. 16, Issue 10, pp. 3891-3902, (2018) (PubMed).
: "Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors." in: Cellular signalling, Vol. 30, pp. 82-91, (2016) (PubMed).
: "Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA)." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11897-905, (2014) (PubMed).
Aliases for SNCA 抗体
synuclein alpha L homeolog (snca.L) 抗体alpha-synuclein (LOC619283) 抗体
synuclein alpha (SNCA) 抗体
synuclein, alpha (Snca) 抗体
synuclein alpha (Snca) 抗体
alphaSYN 抗体
LOC619283 抗体
MGC64356 抗体
NACP 抗体
PARK1 抗体
PARK4 抗体
PD1 抗体
snca 抗体
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