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SMURF2 ELISA试剂盒

(SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3. In this way, SMAD2 may recruit substrates, such as SNON, for ubiquitin-mediated degradation. Enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2. Coexpression of SMURF2 with SMAD1 results in considerable decrease in steady-state level of SMAD1 protein and a smaller decrease of SMAD2 level (By similarity).

3 results :

SMURF2 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
产品编号 ABIN6970246
 
SMURF2 适用: 大鼠 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Cell Lysate, Tissue Homogenate
产品编号 ABIN6959517
 
SMURF2 适用: 小鼠 Colorimetric
产品编号 ABIN1131328
 
  • 类型 Kit
    • Kit
  • 应用范围 ELISA
    • ELISA
  • 适用
    • Human
    • Mouse
    • Rat
  • 图像
  • 实验类型
    • Sandwich ELISA
  • Analytical Method
    • Quantitative
  • 检测方法
    • Colorimetric
  • Plate
    • Pre-coated
  • 标记
    • 非结合性
  • 样本
    • Tissue Homogenate
    • Cell Lysate
    • Plasma
    • Serum
  • Supplier
    • antibodies-online
    • EIAab

Aliases for SMURF2 ELISA试剂盒

SMAD specific E3 ubiquitin protein ligase 2 (SMURF2) ELISA试剂盒
SMAD specific E3 ubiquitin protein ligase 2 (smurf2) ELISA试剂盒
SMAD specific E3 ubiquitin protein ligase 2 (Smurf2) ELISA试剂盒
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