(Solute Carrier Family 6 (Amino Acid Transporter), Member 14 (Slc6a14))
This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010].
Coothankandaswamy, Cao, Xu, Prasad, Singh, Reynolds, Yang, Ogura, Ganapathy, Bhutia: "Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer." in: British journal of pharmacology, Vol. 173, Issue 23, pp. 3292-3306, (2016) (PubMed).
Penheiter, Erdogan, Murphy, Hart, Felipe Lima, Rakhshan Rohakhtar, OBrien, Bamlet, Wuertz, Smyrk, Couch, Vasmatzis, Bender, Carlson: "Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma." in: BioMed research international, Vol. 2015, pp. 593572, (2015) (PubMed).
Ko, Lin, Flomenberg, Pestell, Howell, Sotgia, Lisanti, Martinez-Outschoorn: "Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance." in: Cancer biology & therapy, Vol. 12, Issue 12, pp. 1085-97, (2012) (PubMed).
González, Martin, Burdsal, Sloan, Mager, Harris, Sutherland: "Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo." in: Developmental biology, Vol. 361, Issue 2, pp. 286-300, (2011) (PubMed).
Aliases for Slc6a14 抗体
solute carrier family 6 member 14 (SLC6A14) 抗体 solute carrier family 6 (neurotransmitter transporter), member 14 (Slc6a14) 抗体 1110007A17Rik 抗体 9030613J17Rik 抗体 ATB0plus 抗体 BMIQ11 抗体 CATB0plus 抗体