Functions as a retroviral receptor for M813 murine leukemia virus (MuLV) entry. Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.
De Paepe, Zschüntzsch, Šokčević, Weis, Schmidt, De Bleecker: "Induction of Osmolyte Pathways in Skeletal Muscle Inflammation: Novel Biomarkers for Myositis." in: Frontiers in neurology, Vol. 9, pp. 846, (2018) (PubMed).
Hernández-Ochoa, Robison, Contreras, Shen, Zhao, Schneider: "Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscle." in: Experimental biology and medicine (Maywood, N.J.), Vol. 237, Issue 9, pp. 1068-83, (2012) (PubMed).
Chau, Lee, Law, Chung, Chung: "Sodium/myo-inositol cotransporter-1 is essential for the development and function of the peripheral nerves." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 19, Issue 13, pp. 1887-9, (2005) (PubMed).
Aliases for SLC5A3 抗体
solute carrier family 5 (inositol transporters), member 3 (Slc5a3) 抗体 solute carrier family 5 member 3 (SLC5A3) 抗体 solute carrier family 5 member 3 (Slc5a3) 抗体 AA623876 抗体 BF642829 抗体 SMIT 抗体 Smit 抗体 Smit1 抗体 SMIT1 抗体 SMIT2 抗体