(Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
Kim, Trussell: "Negative shift in the glycine reversal potential mediated by a Ca2+- and pH-dependent mechanism in interneurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 37, pp. 11495-510, (2009) (PubMed).
Parker, Bouyer, Daly, Boron: "Cloning and characterization of novel human SLC4A8 gene products encoding Na+-driven Cl-/HCO3(-) exchanger variants NDCBE-A, -C, and -D." in: Physiological genomics, Vol. 34, Issue 3, pp. 265-76, (2008) (PubMed).
Aliases for SLC4A8 抗体
solute carrier family 4, sodium bicarbonate cotransporter, member 8 S homeolog (slc4a8.S) 抗体 solute carrier family 4 member 8 (SLC4A8) 抗体 solute carrier family 4, sodium bicarbonate cotransporter, member 8 (slc4a8) 抗体 solute carrier family 4 (anion exchanger), member 8 (Slc4a8) 抗体 solute carrier family 4 member 8 (Slc4a8) 抗体 AW493845 抗体 C230026C11 抗体 kNBC-3 抗体 KNBC3 抗体 NBC3 抗体 NDCBE 抗体 SLC4A8 抗体