This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Ohta, Inoue, Yasujima, Ishimaru, Yuasa: "Functional characteristics of two human MATE transporters: kinetics of cimetidine transport and profiles of inhibition by various compounds." in: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques, Vol. 12, Issue 3, pp. 388-96, (2010) (PubMed).
Tanihara, Masuda, Sato, Katsura, Ogawa, Inui: "Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters." in: Biochemical pharmacology, Vol. 74, Issue 2, pp. 359-71, (2007) (PubMed).
Aliases for SLC47A2 抗体
solute carrier family 47 member 1 (SLC47A1) 抗体 solute carrier family 47 member 2 (Slc47a2) 抗体 solute carrier family 47 member 2 (SLC47A2) 抗体 multidrug and toxin extrusion protein 2 (MGYG_04899) 抗体 multidrug and toxin extrusion protein 2 (LOC100020163) 抗体 multidrug and toxin extrusion protein 2 (LOC100073163) 抗体 solute carrier family 47, member 2 (Slc47a2) 抗体 4933429E10Rik 抗体 DKFZp469G161 抗体 MATE2 抗体 MATE2-B 抗体 MATE2-K 抗体 MATE2K 抗体 RGD1562382 抗体 SLC47A2 抗体