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SLC29A1 产品

(Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

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This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured SLC29A1 Categories

SLC29A1 抗体

High quality antibodies with extensive validation data.

SLC29A1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SLC29A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC29A1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (3)
  • (5)
Cat. No. ABIN387940
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7151966
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7256716
Quantity 200 μL
Datasheet Datasheet

Recommended SLC29A1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970331
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132220
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1132221
Quantity 96 tests
Datasheet Datasheet

Recommended SLC29A1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1778128
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3117666
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130073
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SLC29A1 Products

Niemann, Haufs-Brusberg, Puetz, Feickert, Jaeckstein, Hoffmann, Zurkovic, Heine, Trautmann, Müller, Tönjes, Schlein, Jafari, Eltzschig, Gnad, Blüher, Krahmer, Kovacs, Heeren, Pfeifer: "Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine." in: Nature, (2022) (PubMed).

Russell, Pillarsetty, Kramer, Romesser, Desai, Haimovitz-Friedman, Lowery, Humm et al.: "In Vitro and In Vivo Comparison of Gemcitabine and the Gemcitabine Analog 1-(2'-deoxy-2'-fluoroarabinofuranosyl) Cytosine (FAC) in Human Orthotopic and Genetically Modified Mouse Pancreatic Cancer ..." in: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, (2017) (PubMed).

Hur, Jung, Goo, Moon, Choi, Choi, Chung, Lee: "Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5." in: Oncotarget, Vol. 8, Issue 7, pp. 11748-11762, (2017) (PubMed).

Kim, Lee, Cheong, Koh, Ahn, Kim, Shin, Yoon: "SLC29A1 (ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia." in: Cancer chemotherapy and pharmacology, Vol. 78, Issue 3, pp. 533-40, (2016) (PubMed).

Sasaki, Murakami, Uemura, Sudo, Hashimoto, Kondo, Sueda et al.: "Concurrent analysis of human equilibrative nucleoside transporter 1 and ribonucleotide reductase subunit 1 expression increases predictive value for prognosis in cholangiocarcinoma patients treated ..." in: British journal of cancer, Vol. 111, Issue 7, pp. 1275-84, (2014) (PubMed).

Greenhalf, Ghaneh, Neoptolemos, Palmer, Cox, Lamb, Garner, Campbell, Mackey, Costello, Moore, Valle, McDonald, Carter, Tebbutt, Goldstein, Shannon, Dervenis, Glimelius, Deakin, Charnley, Lacaine et al.: "Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial. ..." in: Journal of the National Cancer Institute, Vol. 106, Issue 1, pp. djt347, (2014) (PubMed).

Nakagawa, Murakami, Uemura, Sudo, Hashimoto, Kondo, Sueda et al.: "Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in ..." in: Surgery, Vol. 153, Issue 4, pp. 565-75, (2013) (PubMed).

Kondo, Murakami, Uemura, Sudo, Hashimoto, Nakashima, Sueda et al.: "Combined analysis of dihydropyrimidine dehydrogenase and human equilibrative nucleoside transporter 1 expression predicts survival of pancreatic carcinoma patients treated with adjuvant gemcitabine ..." in: Annals of surgical oncology, Vol. 19 Suppl 3, pp. S646-55, (2012) (PubMed).

Grenz, Bauerle, Dalton, Ridyard, Badulak, Tak, McNamee, Clambey, Moldovan, Reyes, Klawitter, Ambler, Magee, Christians, Brodsky, Ravid, Choi, Wen, Lukashev, Blackburn, Osswald, Coe, Nürnberg, Haase et al.: "Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. ..." in: The Journal of clinical investigation, Vol. 122, Issue 2, pp. 693-710, (2012) (PubMed).

Ibarra, Jain, Pfeiffer: "Host-based ribavirin resistance influences hepatitis C virus replication and treatment response." in: Journal of virology, Vol. 85, Issue 14, pp. 7273-83, (2011) (PubMed).

Synonyms and alternative names related to SLC29A1

solute carrier family 29 member 1 (Augustine blood group) (SLC29A1), solute carrier family 29 member 1 (Slc29a1), solute carrier family 29 (nucleoside transporters), member 1 (Slc29a1), 1200014D21Rik, AA407560, ENT1, rENT1

Protein level used designations for SLC29A1

  • equilibrative NBMPR-sensitive nucleoside transporter
  • equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter
  • equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter
  • equilibrative nucleoside transporter 1
  • nucleoside transporter, es-type
  • solute carrier family 29 (nucleoside transporters), member 1
  • solute carrier family 29 member 1
  • solute carrier family 29, member 1
  • NBMPR-sensitive equilibrative nucleoside transporter
  • equilibrative nucleoside transporter 1 variant delta 11
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