(Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2))
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
Mishima, Miner, Morizane, Stahl, Sadovsky: "The expression and function of fatty acid transport protein-2 and -4 in the murine placenta." in: PLoS ONE, Vol. 6, Issue 10, pp. e25865, (2011) (PubMed).
Campa, Hüsing, Chang-Claude, Dostal, Boeing, Kröger, Tjønneland, Roswall, Overvad, Dahm, Rodríguez, Sala, Pérez, Larrañaga, Chirlaque, Ardanaz, Khaw, Wareham, Allen, Travis, Trichopoulou, Naska et al.: "Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC). ..." in: European journal of cancer (Oxford, England : 1990), Vol. 47, Issue 3, pp. 420-7, (2011) (PubMed).
Aliases for SLC27A2 抗体
solute carrier family 27 (fatty acid transporter), member 2 L homeolog (slc27a2.L) 抗体 solute carrier family 27 member 2 (SLC27A2) 抗体 solute carrier family 27 (fatty acid transporter), member 2a (slc27a2a) 抗体 solute carrier family 27 (fatty acid transporter), member 2 (slc27a2) 抗体 solute carrier family 27 (fatty acid transporter), member 2 (Slc27a2) 抗体 solute carrier family 27 member 2 (Slc27a2) 抗体 acsvl1 抗体 ACSVL1 抗体 facvl1 抗体 FACVL1 抗体 fatp2 抗体 FATP2 抗体 hFACVL1 抗体 HsT17226 抗体 im:7139614 抗体 slc27a2 抗体 Vlac 抗体 vlacs 抗体 Vlacs 抗体 VLACS 抗体 vlcs 抗体 VLCS 抗体 wu:fb99g05 抗体 zgc:112376 抗体