(Solute Carrier Family 25 (Mitochondrial Carrier, Phosphate Carrier), Member 25 (SLC25A25))
The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012].
del Arco, Satrústegui: "Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24701-13, (2004) (PubMed).
Fiermonte, De Leonardis, Todisco, Palmieri, Lasorsa, Palmieri: "Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30722-30, (2004) (PubMed).
Aliases for SLC25A25 抗体
solute carrier family 25 member 25 (SLC25A25) 抗体 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 (Slc25a25) 抗体 solute carrier family 25 member 25 (Slc25a25) 抗体 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 L homeolog (slc25a25.L) 抗体 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a (slc25a25a) 抗体 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 (slc25a25) 抗体 1110030N17Rik 抗体 MCSC 抗体 Mcsc 抗体 mcsc 抗体 mKIAA1896 抗体 PCSCL 抗体 Pcscl 抗体 pcscl 抗体 RP11-395P17.4 抗体 SCAMC-2 抗体 scamc-2 抗体 scamc2 抗体 slc25a 抗体 slc25a25 抗体 SLC25A25 抗体 wu:fb13d12 抗体 wu:fd14e03 抗体 zgc:77454 抗体