(Sodium Dependent Vitamin C Transporter 1 (SVCT1))
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Subramenium, Sabui, Marchant, Said, Subramanian: "Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB-mediated pathway." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 316, Issue 1, pp. G55-G63, (2019) (PubMed).
Campbell, Vissers, Wohlrab, Hicks, Strother, Bozonet, Robinson, Dachs: "Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice." in: Free radical biology & medicine, Vol. 99, pp. 451-462, (2016) (PubMed).
Subramanian, Nabokina, Patton, Marchant, Moradi, Said: "Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 12, pp. G1079-86, (2013) (PubMed).
Aliases for SLC23A1 抗体
solute carrier family 23 member 1 (SLC23A1) 抗体 solute carrier family 23 (nucleobase transporters), member 1 (Slc23a1) 抗体 solute carrier family 23 member 1 (Slc23a1) 抗体 D18Ucla2 抗体 SLC23A2 抗体 Slc23a2 抗体 SVCT1 抗体 YSPL3 抗体