Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq, Jul 2008].
Hubeny, Keiser, Oswald, Jedlitschky, Kroemer, Siegmund, Grube: "Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 44, Issue 10, pp. 1562-8, (2016) (PubMed).
Salomon, Muchitsch, Gausterer, Schwagerus, Huwer, Daum, Lehr, Ehrhardt: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." in: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, (2014) (PubMed).
Aliases for SLC22A4 抗体
solute carrier family 22 (organic cation/zwitterion transporter), member 4 (slc22a4) 抗体 solute carrier family 22 member 4 (SLC22A4) 抗体 Solute carrier family 22 member 4 (s22a4) 抗体 solute carrier family 22 (organic cation transporter), member 4 (Slc22a4) 抗体 solute carrier family 22 member 4 (Slc22a4) 抗体 Octn1 抗体 OCTN1 抗体 SLC22A4 抗体 zgc:66036 抗体