(Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2))
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM)\; muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010].
custom-made
SLC10A2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
SLC10A2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Al-Hilal, Park, Alam, Chung, Park, Kim, Kwon, Kim, Kim, Byun: "Oligomeric bile acid-mediated oral delivery of low molecular weight heparin." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 175, pp. 17-24, (2014) (PubMed).
Aliases for SLC10A2 蛋白
solute carrier family 10 member 2 (SLC10A2) 蛋白 solute carrier family 10 (sodium/bile acid cotransporter), member 2 (slc10a2) 蛋白 solute carrier family 10 member 2 (Slc10a2) 蛋白 solute carrier family 10, member 2 (Slc10a2) 蛋白 ASBT 蛋白 IBAT 蛋白 ISBAT 蛋白 ISBT 蛋白 NTCP2 蛋白 PBAM 蛋白 zgc:63998 蛋白