SKAP1 产品
(Src Kinase Associated phosphoprotein 1 (SKAP1))
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This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008].
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Featured SKAP1 Categories
Recommended SKAP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (3)
Cat. No.
ABIN563722
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN563721
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856083
Quantity
100 μL
Datasheet
Datasheet
Recommended SKAP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320072
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3076826
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3122182
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SKAP1 Products
: "Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome." in: Blood, Vol. 113, Issue 1, pp. 127-36, (2009) (PubMed).: "SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription." in: Molecular and cellular biology, Vol. 22, Issue 8, pp. 2673-86, (2002) (PubMed).
: "SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40420-7, (2002) (PubMed).
: "FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 15, pp. 8779-84, (1998) (PubMed).
: "SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55." in: FEBS letters, Vol. 435, Issue 1, pp. 55-60, (1998) (PubMed).
: "Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes." in: The Journal of biological chemistry, Vol. 272, Issue 26, pp. 16077-80, (1997) (PubMed).
Synonyms and alternative names related to SKAP1
src family associated phosphoprotein 1 (Skap1), src kinase associated phosphoprotein 1 (SKAP1), src kinase associated phosphoprotein 1 (Skap1), 1700091G21Rik, Scap1, SCAP1, Skap-55, SKAP55, Skap55Protein level used designations for SKAP1
- ortholog of human src family associated phosphoprotein 1 SCAP1
- src family-associated phosphoprotein 1
- src kinase-associated phosphoprotein 1
- SKAP-55
- pp55
- src family associated phosphoprotein 1
- src kinase-associated phosphoprotein of 55 kDa
- SKAP55 adapter protein
- SKAP55 adaptor protein
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