This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008].
Thalappilly, Suliman, Gayet, Soubeyran, Hermant, Lecine, Iovanna, Dusetti: "Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach." in: Proteomics, Vol. 8, Issue 15, pp. 3071-81, (2008) (PubMed).
Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Aliases for SH3BP4 抗体
SH3 domain binding protein 4 (SH3BP4) 抗体 SH3-domain binding protein 4 (Sh3bp4) 抗体 SH3-domain binding protein 4 (sh3bp4) 抗体 SH3-domain binding protein 4 L homeolog (sh3bp4.L) 抗体 SH3 domain binding protein 4 (Sh3bp4) 抗体 AI594717 抗体 AW227605 抗体 BOG25 抗体 bog25 抗体 LOC569399 抗体 SH3BP4 抗体 sh3bp4 抗体 TTP 抗体 ttp 抗体