小鼠 anti-人 Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antibody
Igk
IHC (p)
Monoclonal
SPM508
IgG1
unconjugated
产品编号 ABIN7879474
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for 小鼠 anti-人 Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antibody (ABIN7879474)
抗原
Igk
(Immunoglobulin kappa Chain Complex (Igk))
克隆类型
单克隆
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
SPM508
亚型
IgG1, kappa
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抗原表位
- Light Chain
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适用
- 人
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宿主
- 小鼠
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原理
- Kappa Light Chain Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human B-lymphoma cells were used as the immunogen for this Kappa Light Chain antibody.
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应用备注
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The optimal dilution of the Kappa Light Chain antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Kappa Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Igk (Immunoglobulin kappa Chain Complex (Igk))
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别名
- Kappa
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背景
- This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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UniProt
- P01601
抗原
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