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小鼠 anti-人 IgM (Heavy Chain) Antibody

Carrier-free ELISA Monoclonal IGHM-1623 IgG1 unconjugated
产品编号 ABIN7879457
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for 小鼠 anti-人 IgM (Heavy Chain) Antibody (ABIN7879457)

抗原

IgM

克隆类型

  • 600
  • 240
单克隆

应用范围

  • 512
  • 458
  • 438
  • 298
  • 270
  • 117
  • 91
  • 91
  • 62
  • 62
  • 45
  • 35
  • 34
  • 29
  • 21
  • 21
  • 12
  • 9
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA

质量等级

Carrier-free

克隆位点

IGHM-1623

亚型

IgG1, kappa
  • 抗原表位

    • 198
    • 103
    • 25
    • 12
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Heavy Chain

    适用

    • 292
    • 204
    • 88
    • 57
    • 42
    • 41
    • 39
    • 30
    • 28
    • 22
    • 17
    • 14
    • 13
    • 13
    • 8
    • 4
    • 2

    宿主

    • 401
    • 246
    • 213
    • 24
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    小鼠

    原理

    IgM Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    The heavy chain of human IgM was used as the immunogen for the IgM antibody.
  • 应用备注

    Optimal dilution of the IgM antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the IgM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IgM

    物质类

    Antibody

    背景

    Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

    UniProt

    P01871
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