小鼠 anti-人 IgM (Heavy Chain) Antibody
IHC (p)
Monoclonal
SPM557
IgG1
unconjugated
产品编号 ABIN7879450
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for 小鼠 anti-人 IgM (Heavy Chain) Antibody (ABIN7879450)
抗原
IgM
克隆类型
单克隆
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
SPM557
亚型
IgG1, kappa
-
-
抗原表位
- Heavy Chain
-
适用
- 人
-
宿主
- 小鼠
-
原理
- IgM Antibody
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Recombinant heavy chain of human IgM was used as the immunogen for this IgM antibody.
-
-
-
-
应用备注
-
The optimal dilution of the IgM antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the IgM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- IgM
-
物质类
- Antibody
-
背景
- Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
-
UniProt
- P01871
抗原
-
You are here:
