小鼠 anti-人 IgG (Heavy Chain) Antibody (CF®488A)
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北京 101111
Quick Overview for 小鼠 anti-人 IgG (Heavy Chain) Antibody (CF®488A) (ABIN7879449)
抗原
克隆类型
标记
应用范围
克隆位点
亚型
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抗原表位
- Heavy Chain
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适用
- 人
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宿主
- 小鼠
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原理
- IgG Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Purified human IgG heavy chain was used as the immunogen for this anti-IgG antibody.
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Mouse anti-Human IgG (Fc Region) antibody
Animal-Free ELISA, WB, FACS, IF Multiclonal IgG2a Recombinant Antibody unconjugated
Mouse anti-Human IgG (Fc Region) antibody (HRP)Animal-Free ELISA, WB, FACS, IF Multiclonal IgG2a Recombinant Antibody HRP
Mouse anti-Human IgG (Fab Region) antibody (PE)FACS Monoclonal 4A11 IgG1 PE
Rabbit anti-Human IgG (AA 167-185), (Internal Region) antibodyIHC (p) Monoclonal E20-V IgG unconjugated
Mouse anti-Human IgG (Fc Region) antibody (APC)ELISA, FACS Monoclonal H2 IgG2b APC
Donkey anti-Human IgG (Heavy & Light Chain) antibody (Texas Red (TR)) - PreadsorbedFACS, FLISA, FM Polyclonal IgG Texas Red (TR)
Mouse anti-Human IgG (Fc Region) antibody (Alexa Fluor 555)Animal-Free ELISA, WB, FACS, IF Multiclonal IgG2a Recombinant Antibody Alexa Fluor 555
Mouse anti-Human IgG (Fc Region) antibody (Alexa Fluor 488)Animal-Free ELISA, WB, FACS, IF Multiclonal IgG2a Recombinant Antibody Alexa Fluor 488
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应用备注
- Optimal dilution of the IgG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the IgG antibody at 2-8oC, protected from light.
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- IgG
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物质类
- Antibody
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背景
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Immunoglobulin gamma (IgG) is the most common class of antibody in blood and extracellular fluid. Approximately 75 % of serum antibodies in humans are IgG. There are four immunoglobulin gamma subclasses: one, two, three and four. IgG1 is the most common, with 68 % of all gamma class antibodies being G1, and G4 is the least common at 4 %. Gamma class antibodies are found primarily in the secondary immune response, class switching from IgM and IgD. They are the only class of antibody that can cross the placenta, and along with IgA secreted in breast milk, provide the neonate with humoral immunity before immune system development occurs.
This antibody recognizes a protein of 75 kDa identified as the gamma heavy chain of human immunoglobulins. It does not cross-react with alpha, mu, epsilon, or delta heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The IgG antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
抗原
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