Recombinant 兔 anti-人 IgA (full length) Antibody
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Quick Overview for Recombinant 兔 anti-人 IgA (full length) Antibody (ABIN7878393)
抗原
抗体类型
克隆类型
应用范围
质量等级
克隆位点
亚型
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抗原表位
- full length
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适用
- 人
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宿主
- 兔
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原理
- Human IgA Antibody (Heavy chain) (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human IGHA1 and IGHA2 proteins were used as the immunogen for the human IgA antibody.
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Mouse anti-Human IgA (Heavy Chain) antibody
ELISA, WB, IHC (fro), IP Monoclonal Mc24-2E11 IgG1 unconjugated
Goat anti-Human IgA (Heavy Chain) antibody (Alkaline Phosphatase (AP))ELISA, WB Polyclonal IgG Alkaline Phosphatase (AP)
Rabbit anti-Human IgA (Chain alpha), (Heavy Chain) antibodyELISA, IHC, WB unconjugated
Goat anti-Human IgA (Heavy Chain) antibody (Biotin)ELISA, WB, FACS Polyclonal IgG Biotin
Goat anti-Human IgA (Heavy Chain) antibody (HRP)ELISA, WB Polyclonal IgG HRP
Mouse anti-Human IgA antibodyELISA, IHC (p) Monoclonal AD2-947 IgG1 unconjugated
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应用备注
- Optimal dilution of the human IgA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the human IgA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IgA
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物质类
- Antibody
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背景
- This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with both IgA1 and IgA2 subclasses of Alpha heavy chain. It reacts with the third constant domain (CH3) of the alpha chain of IgA molecules. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces.The most common feature of plasmacytomas, and certain non-Hodgkin s lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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UniProt
- P01876
抗原
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