兔 anti-人 IgG4 Antibody
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- 抗原 See all IgG4 products
- IgG4
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Full length protein
- 克隆位点
- 1A8
- 亚型
- IgG
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Rabbit anti-Human IgG4 (AA 222-327) antibody
WB, IHC, IP, IF/ICC Polyclonal unconjugated
Mouse anti-Human IgG4 (pFc' Region) antibody (HRP)WB, ELISA, IHC Monoclonal HP6023 IgG3 HRP
Mouse anti-Human IgG4 (pFc' Region) antibody (Alkaline Phosphatase (AP))WB, ELISA, IHC Monoclonal HP6023 IgG3 Alkaline Phosphatase (AP)
Mouse anti-Human IgG4 (Fc Region) antibody (HRP)WB, ELISA, IHC Monoclonal HP6025 IgG1 HRP
Mouse anti-Human IgG4 (Fc Region) antibody (Alkaline Phosphatase (AP))WB, ELISA, IHC Monoclonal HP6025 IgG1 Alkaline Phosphatase (AP)
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- IgG4
- Abstract
- IgG4 产品
- 物质类
- Antibody
- 背景
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Synonyms: Ig gamma-4 chain C region, IGHG4, Immunoglobulin heavy constant gamma 4
Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
- UniProt
- P01861
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