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大鼠 anti-人 IgA Antibody

ELISA, ELISpot Monoclonal MT57 IgG2a unconjugated
产品编号 ABIN6963994
发货至: 中国

Quick Overview for 大鼠 anti-人 IgA Antibody (ABIN6963994)

抗原

IgA

克隆类型

  • 308
  • 71
单克隆

应用范围

  • 193
  • 145
  • 130
  • 107
  • 107
  • 104
  • 61
  • 47
  • 47
  • 34
  • 28
  • 26
  • 23
  • 18
  • 16
  • 16
  • 14
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, ELISpot

克隆位点

MT57

亚型

IgG2a
  • 适用

    • 188
    • 61
    • 45
    • 16
    • 15
    • 13
    • 13
    • 12
    • 12
    • 11
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1

    宿主

    • 201
    • 109
    • 58
    • 17
    • 13
    • 6
    • 2
    大鼠

    特异性

    Fc part of native IgA.

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with IgA from non-human primates.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Human IgA
  • 应用备注

    For quantification of IgA in serum, plasma and cell culture supernatants using ELISA and for enumeration of IgA (total and antigen-specific) producing cells using ELISpot. Human IgA: In ELISA, MT57 is recommended as coating mAb in combination with ALP-conjugated detection mAb MT20 .

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing. The expiry date indicates how long unopened products, stored according to instructions, are recommended for use.

    有效期

    18 months
  • Colombo, Pereira, da Silva, Ribas, Parisotto, Mattos-Graner, Smith, Duque: "Relationship between the IgA antibody response against Streptococcus mutans GbpB and severity of dental caries in childhood." in: Archives of oral biology, Vol. 67, pp. 22-7, (2017) (PubMed).

    Klippert, Neumann, Stahl-Hennig: "Comparative phenotypical analysis of B cells in fresh and cryopreserved mononuclear cells from blood and tissue of rhesus macaques." in: Journal of immunological methods, Vol. 433, pp. 59-68, (2017) (PubMed).

    Bankó, Pozsgay, Szili, Tóth, Gáti, Nagy, Rojkovich, Sármay: "Induction and Differentiation of IL-10-Producing Regulatory B Cells from Healthy Blood Donors and Rheumatoid Arthritis Patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 4, pp. 1512-1520, (2017) (PubMed).

    Järnum, Bockermann, Runström, Winstedt, Kjellman: "The Bacterial Enzyme IdeS Cleaves the IgG-Type of B Cell Receptor (BCR), Abolishes BCR-Mediated Cell Signaling, and Inhibits Memory B Cell Activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 12, pp. 5592-601, (2016) (PubMed).

    De Bruyne, Bogaert, De Ruyck, Lambrecht, Van Winckel, Gevaert, Dullaers: "Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells." in: Clinical and experimental immunology, Vol. 180, Issue 3, pp. 542-50, (2015) (PubMed).

  • 抗原

    IgA

    物质类

    Antibody

    基因ID

    3494, 3493
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