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小鼠 anti-人 Ig (Chain kappa), (Light Chain) Antibody

FACS Monoclonal TB28-2 IgG1 unconjugated
产品编号 ABIN614821
发货至: 中国

Quick Overview for 小鼠 anti-人 Ig (Chain kappa), (Light Chain) Antibody (ABIN614821)

抗原

Ig

克隆类型

  • 123
  • 95
单克隆

应用范围

  • 173
  • 138
  • 101
  • 69
  • 57
  • 26
  • 22
  • 12
  • 12
  • 7
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

TB28-2

亚型

IgG1
  • 抗原表位

    • 80
    • 78
    • 63
    • 38
    • 4
    • 2
    • 1
    Chain kappa, Light Chain

    适用

    • 118
    • 63
    • 20
    • 18
    • 9
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1

    宿主

    • 102
    • 77
    • 39
    • 18
    • 3
    • 1
    • 1
    小鼠

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Human IgG-kappa myeloma protein
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Storer the antibody at 2-8 °C for up to one month or (in aliqouts) at -20 °C for longer.
  • Jourdan, Caraux, De Vos, Fiol, Larroque, Cognot, Bret, Duperray, Hose, Klein: "An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization." in: Blood, Vol. 114, Issue 25, pp. 5173-81, (2009) (PubMed).

    Böttcher, Ritgen, Buske, Gesk, Klapper, Hoster, Hiddemann, Unterhalt, Dreyling, Siebert, Kneba, Pott et al.: "Minimal residual disease detection in mantle cell lymphoma: methods and significance of four-color flow cytometry compared to consensus IGH-polymerase chain reaction at initial staging and for ..." in: Haematologica, Vol. 93, Issue 4, pp. 551-9, (2008) (PubMed).

    Cassens, Göhde, Kuling, Gröning, Schlenke, Lehman, Traoré, Servais, Henin, Reichelt, Greve: "Simplified volumetric flow cytometry allows feasible and accurate determination of CD4 T lymphocytes in immunodeficient patients worldwide." in: Antiviral therapy, Vol. 9, Issue 3, pp. 395-405, (2004) (PubMed).

    Karandikar, Aquino, McKenna, Kroft: "Transient myeloproliferative disorder and acute myeloid leukemia in Down syndrome. An immunophenotypic analysis." in: American journal of clinical pathology, Vol. 116, Issue 2, pp. 204-10, (2001) (PubMed).

    Nakamura, Kubagawa, Cooper: "Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8522-6, (1992) (PubMed).

  • 抗原

    Ig

    别名

    Immunoglobulin

    背景

    Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
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