小鼠 anti-人 IgA (Free & Bound), (Secretory Component) Antibody (TRITC)
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- 抗原 See all IgA products
- IgA
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抗原表位
- Free & Bound, Secretory Component
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- TRITC
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 产品特性
- Molar Ratio: 2.4 moles TRITC per mole of Rabbit IgG.
- 免疫原
- Highly purified Secretory component isolated from Human milk.
- 克隆位点
- NI 194-4 (A89-039)
- 亚型
- IgG1
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Absorption / Emission: 550 nm / 570 nm
- 限制
- 仅限研究用
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- 溶解方式
- Restore by adding 0.5 mL sterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2
- 浓度
- 0.4 mg/mL
- 缓冲液
- PBS, pH 7.2 without preservatives. No foreign protein added.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated thawing and freezing. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody lyophilized at 2-8 °C for one month or (in aliquots) at -28 °C for longer. Diluted ascites should be stored at 2-8 °C, not refrozen, and preferably used the same day.
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- 抗原
- IgA
- Abstract
- IgA 产品
- 物质类
- Antibody
- 背景
- Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A
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