小鼠 anti-人 IgA (Free & Bound), (Secretory Component) Antibody (FITC)
Quick Overview for 小鼠 anti-人 IgA (Free & Bound), (Secretory Component) Antibody (FITC) (ABIN567757)
抗原
克隆类型
标记
应用范围
克隆位点
亚型
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抗原表位
- Free & Bound, Secretory Component
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适用
- 人
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宿主
- 小鼠
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交叉反应 （详细）
- Species reactivity (tested):Human.
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产品特性
- Molar Ratio: Fluorochrome/IgG: aprox. 2.0
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免疫原
- Highly purified Secretory component isolated from Human milk.
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Mouse anti-Human IgA (Heavy Chain) antibody
ELISA, WB, IHC (fro), IP Monoclonal Mc24-2E11 IgG1 unconjugated
Goat anti-Human IgA (Heavy Chain) antibody (Biotin)ELISA, WB, FACS Polyclonal IgG Biotin
Goat anti-Human IgA (Heavy Chain) antibody (Alkaline Phosphatase (AP))ELISA, WB Polyclonal IgG Alkaline Phosphatase (AP)
Rabbit anti-Human IgA (Chain alpha), (Heavy Chain) antibodyELISA, WB, IHC unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Absorption / Emission: 492 nm / 515 nm
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限制
- 仅限研究用
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溶解方式
- Restore by adding 0.5 mL sterile distilled water.
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浓度
- 0.4 mg/mL
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缓冲液
- PBS, pH 7.2 without preservatives and foreign proteins.
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储存液
- Without preservative
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注意事项
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Product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing. -
储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one week or (in aliquots) at -28 °C for longer.
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- IgA
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物质类
- Antibody
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背景
- Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A
抗原
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